OMX | Organic Metabolomics
Advanced Organic Acids and Amino Acids Profile
OMX EDUCATION
FAQs | News + Reviews | Videos
Learn to successfully use the OMX Test in clinical practice
Take advantage of these valuable resources from the best of OMX training and education.
Companion download resources are also available for reference.
OMX Provides a New Framework of Healthcare
Current healthcare practices tend to be reactive and based on infrequent assessment of markers that diagnose frank disease. Characterizing an individual’s metabolomic, genomic, and microbiome status at baseline for comparison purposes over time will ideally become the new framework of healthcare.
As just one example, the benefits of incorporating metabolomics can be seen in the assessment of inborn errors of metabolism. For decades, traditional organic acids testing has been the standard for this screening, but it has limitations. Recent research identified that metabolomic profiling of inborn errors was found to have a six-fold higher diagnostic rate and can screen for significantly more metabolic diseases, when compared to traditional newborn screening.
OMX Helps to Translate Metabolomics Research into Clincal Care
Metabolomics research has generally compared sick or disease populations to healthy controls and identified the analytes, pathways, or categories that were most impacted. The research has concentrated on several conditions, including diabetes, autism, Alzheimer’s disease, obesity, fatty-liver disease, heart disease, toxic exposure, and more.
Emerging research is beginning to characterise core metabolic signatures and increase the understanding of biochemical relationships within different conditions or diseases. The OMX metabolomics test allows clinicians to identify markers or pathways that research has identified as most associated with specific diseases or core impairments.
NEW: OMX Metabolomics Course
with Dr Oscar Coetzee
Gain in-depth knowledge to evaluate and interpret the OMX Test
OMX FAQs
Accuracy of the OMX Test
Q: How accurate is the OMX test and what technology is being used?
A: OMX uses the latest in small molecule technology, called a triple quadrupole tandem mass spectrometer. High-performance liquid chromatography (HPLC) separation followed by a tandem mass spectrometer (LC MS/MS), this technique is uniquely suited to accurately detect and quantify small molecules. LC MS/MS is used primarily by research, pharmaceutical companies, commercial laboratories, and more recently by clinical laboratories. It is superior to immunoassays or conventional high-performance liquid chromatography (HPLC) for low molecular weight analytes and has higher throughput than gas chromatography-mass spectrometry (GC MS).
Why choose the OMX over other tests
Q: What makes OMX different from other tests on the market?
A:Additions of the following valuable markers that are not yet available on other Organic Acids Tests:
- Kynurenine and Kynurenine/Tryptophan Ratio (KT Ratio)
- Urinary cortisol
- Includes glucose and fructose for carbohydrate intake and metabolic assessment
- Increased detection of fatty acid and oxidation markers
- Collagen Catabolism Markers
- Plant compounds
- Microalbumin
- GABA
- Equol
Dosage Duration for Product Prescriptions
Q: What suggestions are there for what order and length each product needs to be used with respect to OMX markers falling outside the reference range to get the best results. Does DFH/ DSL have any information about this?
A: Generally, this information can be found in the OMX interpretation guide. You can access the interpretation guide on the OMX Resources Page along with further educational downloads. Keep in mind, the duration of treatment may vary from person to person depending on the organisms found and the severity of the report findings.
OMX Pricing
Q: How much does the OMX test cost from Designs for Health, Australia?
A: $380.00 AUD is the total amount charged for the OMX test. You have the ability to pay for this amount yourself or have your patient pay DFH directly.
OMX report interpretation support
Q: How do I book personalised interpretation support for patient reports?
A: TheDesigns for Health, Australia team are passionate about assisting our practitioners with their patients’ OMX reports, We offer tailored support to make the report findings very relevant for all involved. Feel free to reach out to your expert DFH Health Educator, who will be able to assist you with your patient reports. Alternatively, you can schedule a FREE 15-minute appointment with our technical support team HERE…
Patient timing for OMX collection
Q: When should a patient undertake this test? What are some interfering factors that would make this test inappropriate, or affect the results?
A: Avoid consuming fruits, jams, and jellies for 48 hours prior to collecting the sample. The sample needs to be collected on a Sunday and then sent the following day (Monday).
Lab location, sample delivery, and sample viability
Q: Where is the lab facility located and how does the sample get there in time?
A: Designs for Health Australia (DFH) have partnered with Diagnostic Solutions Laboratory (DSL), the highly reputable and CLIA certified lab facility in Alpharetta, USA. After collection, your patient’s sample will be promptly delivered to DFH in North Manly, Australia. It is then packaged and sent to DSL via express shipment in a temperature-controlled environment to ensure the sample remains viable for testing on arrival at DSL. If for some reason the sample becomes unviable during transit, DFH will contact you promptly and organise for a complimentary kit to be supplied to your patient for re-collection.
OMX report lead time/turnaround
Q: How quickly will my patient’s report become available from the date they send their sample?
A: Some by FDA standards, others by a combination of literature, population studies and datasets.
OMX report access when available
Q: Where do I go to access my patient’s OMX report?
A: You will be prompted to access your patient’s report through the Diagnostic Solutions Lab (DSL) web portal. For a first-time order of the OMX or GI-MAP test, DSL will email you directly with an activation link to set up your portal access. After setting up your access to the DSL portal, you will be prompted by email every time a patient’s report is ready to download from the DSL website.
For all OMX ordering and technical support, please use the DFH website. You will only need to use the DSL portal to download your patient reports.
NOTE: DFH Australia and DSL both have different website access points – designsforhealth.com.au | diagnosticsolutionslab.com
Other complementary functional tests to use alongside OMX
Q: Are there other functional tests that can be used to complement the OMX test in the clinic?
A: Yes, the OMX test is a comprehensive Metabolomics test that illuminates countless areas of physiology. There are other functional tests that can offer great benefits to use alongside OMX, depending on the results you are presented with. Stool testing (GI-MAP) can further qualify GIT-related markers and findings from the OMX to assist with tailored treatments. DNA testing is another great way to further elaborate or confirm findings from an OMX report. Hair and Tissue Mineral Analysis can also additional support.
For all OMX ordering and technical support, please use the DFH website. You will only need to use the DSL portal to download your patient reports.
OMX | Video Introductions and Trainings
Applied Metabolomics with OMX Testing
Presented by Dan Kalish, DC, IFMCP
Dr Dan Kalish presents the Metabolomics Masterclass Series. Here, Dr Kalish explains how organic acid testing using the OMX™ Organic Metabolomics test can offer insight into a wide array of your patients’ health concerns. Dr Kalish uses case studies to illustrate how organic acid testing can be used to establish a baseline metabolic signature for healthy patients and identify dysfunction in patients who may be suffering from:
- Metabolic dysfunction: prediabetes and non-alcoholic fatty liver disease (NAFLD)
- Nutritional deficiencies
- Mood issues (anxiety and depression)
- Gastrointestinal complaints
Metabolomics 101 – An Introduction to Advanced Metabolomics Testing
Presented by Dan Kalish, DC, IFMCP
Dr Dan Kalish teaches practitioners how to apply metabolomics testing into day-to-day practice. While the subject matter is quite complex, even a beginner can use metabolomics testing for any and all patients – whether their chief complaints are fatigue, weight gain, lack of concentration, poor sleep or chronic pain.
Dr Kalish shares:
- What the OMX™ Organic Metabolomics test can show you about your patient’s health status
- The ultimate analysis for metabolic disorders ranging from obesity and weight gain to atherosclerosis, high blood pressure, depression, anxiety and fatigue
- To understand how metabolomics testing can help you understand physiological disruptions that create symptoms
- Simple, clear solutions based on lab data
Beyond Organic Acids – Gut Health with Metabolomics
Presented by Betsy Redmond, PhD. MMSc, RD
Join Dr Redmond for an exciting presentation discussing the role metabolomic testing plays in evaluating gut health.
Metabolomics can help clinicians better identify areas of concern and reveal early dysfunctions. Organic acids and amino acids can inform gut health and function, aiding clinicians in interpreting individual or combinations of metabolites.
In this presentation, Dr Redmond will help practitioners understand how the OMX™ Organic Metabolomics test can evaluate gut health and guide treatment. Watch to learn:
- The impacts of microbial metabolism on aromatic amino acids and polyphenols
- The role of urinary 5-Hydroxyindolacetic acid in irritable bowel syndrome
- The impact of plasma citrulline levels on enterocyte function
- About hippuric acid and its positive correlation with gut species richness
- How incorporating GI-MAP® stool testing with organic and amino acid assessment can provide further insight into gut health
Developments in Metabolomics – Dietary Insights & Impacts for Clinical Practice
Presented by Betsy Redmond, Ph.D., MMSc, RDN
Precision nutrition utilises -omics techniques to personalise diets. Organic metabolomic testing plays a key role in clinical practice. It identifies current individual biological status that reflects diet, lifestyle, genetics, and gut bacteria to reveal a patient’s metabolic signature.
Different foods and diets are associated with specific metabolic fingerprints. For example, vegetarian diets are generally higher in citrate, while the Western diet is associated with high levels of branched-chain amino acids and aromatic amino acids. During this presentation, Betsy Redmond, Ph.D., MMSc, RDN, discusses the latest research on the impact different types of diets have on patient health.
While dietary assessment remains an important tool, incorporating organic metabolomics testing into clinical practice can help practitioners optimise outcomes by identifing how foods and nutrients are processed, their impact on the gut microbiome, and an individual’s specific nutrient needs.
Organic Acid and Amino Acid Testing – Applying Metabolomics in Practice
Presented by Dan Kalish, DC, IFMCP
Metabolomics Masterclass Series – Dr Dan Kalish walks practitioners through the most common applications of metabolomics testing. Learn to identify and reverse chronic inflammatory states that are often present in patients with chronic health complaints.
The OMX™ Organic Metabolomics Profile offers an exciting way to evaluate the health and functioning of each individual’s metabolic pathways. Learn to apply metabolomics in clinical practice to create science-based, natural solutions that can optimize health.
Dr Kalish reviews:
- The role of amino acids in protein synthesis and various body functions
- How B vitamins factors into energy production, cardiovascular health, and insulin resistance
- The impact neurotransmitters have on anxiety, depression, sleep disturbance
- How beta-oxidation can be the missing link in fatigue and weight loss resistance cases
- How to use the OMX test to personalize protocols that optimize patient outcomes
How Advanced Stool Testing Can Offer Deeper Insight into Metabolomics
Presented by Dan Kalish, DC, IFMCP
Join Dr Dan Kalish to connect the dots between the GI-MAP test and the Microbial Metabolites section of the OMX™ Organic Metabolomics test.
Combining the analysis of GI-MAP markers including pathogens, yeast, commensal, and dysbiotic bacteria with the microbial metabolite markers from the OMX test makes for ever more impactful and life-changing patient outcomes.
Watch to learn:
- To integrate the GI-MAP test with the Microbial Metabolites section of the OMX test to yield greater insight into the role diet and the microbiome plays in your patients’ problems
- How commensal bacterial markers relate to polyphenol consumption and polyphenol-based markers on the OMX test
- How to look at the gut-brain connection and see how inflammation coming from the gut can impact a variety of metabolic functions in the rest of the body
Communication Skills for Practitioners
Presented by Dan Kalish, DC, IFMCP
Given the high value of the quality functional tests offered by Designs for Health and their importance to support comprehensive diagnoses and protocols, it is a valuable skill for practitioners to communicate to patients why it is worth investing in these tests.
Dan Kalish is a passionate advocate for practitioners to introduce these tests effectively. He gains valuable diagnostic insights, even before a first patient appointment.
In this brief video Dr Kalish shares “The Ruin Method” for how to introduce higher-priced services.